AntiCancer, Inc. 7917 Ostrow Street, San Diego, CA 92111 USA
Telephone: (858)654-2555; E-mail:
L-methionine a-deamino-g-mercaptomethane lyase, L-methionine- g-lyase.
L-Methionine-g-lyase (METase) is a pyridoxal phosphate- containing enzyme which degrades L-methionine to a-ketobutyrate, ammonia and methyl mercaptan.
Recombinant L-Methionine-g-lyase(rMETase) has been shown to be a broad-bases tumor-selective chemotherapy agent and has synergetic effects with traditional chemotherapy [1-8].
Recombinant L-Methionine-g-lyase (rMETase) is cloned from Pseudomonas putida, expressed in E. coli .
The purity of rMETase is 95% and is supplied as a lyophilized powder and stored at -20°C.